Researchers from the HHMI Janelia Research Campus have developed a technique for chronic jugular microdialysis that enables continuous sampling of blood chemistry in freely moving mice. They will present the technique in a webinar hosted by CMA on March 25, 2026 at 10:00a (Eastern).
The equipment used for the technique features a probe designed specifically for the application by CMA. The probe is designed to attach to Instech’s two channel Vascular Access Button™, which exteriorizes the inlet and outlet channels on the back of the mouse, and connects to the swivel using a specially-designed looped-wire tether.
Ordering Information
| Description | Manufacturer | Part No. |
| Probe and Accessories | ||
| MD blood probe, 3mm, 6kDa | CMA | 8022701 |
| Tubing adapters, 10/pkg | CMA | 3409500 |
| FEP tubing, 1m, 10/pkg | CMA | 8409501 |
| Perfusion fluid T1 7.5mLx10 | CMA | P000034 |
| Caging and Swivel | ||
| CMA mouse cage | CMA | 8012600 |
| Counter-balanced lever arm for mice, 3.5in | Instech | SMCLA |
| Low-torque dual channel quartz-lined swivel | Instech | 375/D/22QM |
| Vascular Access Buttons™, Tether and Accessories | ||
| VAB for mice, 2 channel, 25ga, felt | Instech | VABM2JB/25R25 |
| VAB for mice, 2 channel, 25ga, silicone mesh | Instech | VABM2JBSM/25R25 |
| Looped wire tether for 2 channel mouse VAB, 22ga connectors, 12in | Instech | VABM2T/22MD-12 |
| Protective aluminum caps for 2ch mouse VAB, 5pc | Instech | VABM2JC-5 |
| PinPort injectors, 10 sterile pouches of 5 (50 pcs) | Instech | PNP3M-50 |
| Handling tool for mouse VABs | Instech | VABMG |
| Instruments | ||
| CMA 270 refrigerated fraction collector | CMA | 8011270 |
| Model 400 syringe infusion pump for research | Instech | P400 |
Reference
"Reconstructing a physiological state space via chronic jugular microdialysis in freely moving mice."
Michele Nardin, Nan Wang, Soad Elziny, Claire Boyer, Vojko Pjanovic, Luisa Schuster, Peter Boklund, Sarah Lindo, Kendra Morris, Anoj Ilanges, Jakob Voigts, Emily Jane Dennis
bioRxiv 2025.12.08.692974; doi: https://doi.org/10.64898/2025.12.08.692974