When you need to take repeated blood samples from a rat, consider placing a catheter in the jugular vein or carotid artery and connecting it to a transcutaneous skin button. This method is a refinement over stress-inducing tail vein, jugular or retro-orbital bleeds or other peripheral methods. The Vascular Access Button™ creates a closed system with patency that can extend for weeks and even months.
Furthermore, with a protective aluminum cap, rats can be socially housed, a welfare benefit that is not possible with animals with simple externalized catheters.
Access the button with a syringe fitted with the mating PNP3M injector. Optionally, collect precise microsamples directly into Sarstedt capillary collection tubes by using the PNP3MS connector. For best results always use positive pressure technique when accessing catheters.
To reduce stress even further, collect samples outside the cage: hands-off blood sampling.