Instech Blog

DIY Research: Vascular Access Challenges and Solutions


Amy Martunas, CVT, RLATG, SRA, SRT, Instech Global Director, Preclinical Application Support and Lena Medina, RLATG, Instech Sales Director, North America discuss the following topics in this 48 minute long radio-talk-show like webinar:

DIY Catheters and the Fluid Pathway

  • Why sterility is important and sterile cut tubing segments
  • Catheter tip shape and its resulting impact on patency
  • Long-term patency goals
  • Contamination and how it relates to patency failure
  • Subclinical infections and how they impact study outcomes, animal welfare, and scientific data
  • When it is or isn't acceptable to use non-sterile products

Vascular Access Buttons

Sterile Solutions

  • Making your own catheter lock and flush solutions - when is it ok?
  • Definition of sterile, pharmaceutical-grade, USP 797
  • Regulatory guidance and recommendations including animal welfare, USDA, OLAW, and AAALAC


Guide for the Care and Use of Laboratory Animals

Rodent Surgery Application of Aseptic Technique and Perioperative Care

Guidelines for Rodent Survival Surgery

Animal Welfare Act and Animal Welfare Regulations

Patency of Jugular Vein Catheters in CD-1® IGS Mice: Evaluation of Three Catheter Maintenance Schedules in Standardly Externalized Catheter and Transcutaneous Buttons

PHS Policy on Humane Care and Use of Laboratory Animals

Guidelines for the Use of Non-Pharmaceutical Grade Compounds in Laboratory Animals

AAALAC Guidance Pertaining to Non-Pharmaceutical-Grade Compounds

VAB™ and Positive Pressure Technique Can Improve Patency of Rodent Catheters