---
title: Are Open Luer Connections Compromising Your Research?
description: Needlefree luer injection ports to create a closed system at the connection point between your infusion tether and the dosing syringe.
---

[Resources | Blog ](https://www.instechlabs.com/blog)

# [Are Open Luer Connections Compromising Your Research?](https://www.instechlabs.com/blog/from-pump-to-port-an-aseptic-closed-system)

 Written by [Wyatt Boughter](https://www.instechlabs.com/blog/author/wyatt-boughter) | Jul 21, 2022 11:19:44 AM

For research infusing or sampling from laboratory animals, keeping the fluid path sealed off from bacteria and air is critical for maintaining patency and avoiding infection. If you are using a [Vascular Access Button](https://www.instechlabs.com/blog/guide-to-vascular-access-buttons)™ instead of an externalized catheter you have solved the problem at the animal connection point. But what about the connection to your syringe? An open luer connection defeats the [closed system](https://www.instechlabs.com/hubfs/assets/videos/closed-vs-open.mp4), particularly if you are changing syringes during a study. You could use a [PinPort](https://www.instechlabs.com/products/tubing-connectors-pinports/pinports)™ connection, but these are not designed to lock together the way luers do. The needlefree Rymed® luer connector solves this problem, and it's [now available from Instech](https://www.instechlabs.com/products/tubing-connectors-pinports/connectors/rymed).

### How it Works

The [Rymed InVision-Plus®](https://www.instechlabs.com/products/tubing-connectors-pinports/connectors/rymed) port seals when disconnected, but opens when connected to the male luer on a syringe. You can use aseptic technique, swabbing the septum, prior to connection. The port has a 27 microliter priming volume, but almost magically it does not pull back fluid when disconnecting or push it forward when connecting: it has neutral fluid displacement. 

 

 

[View full post](https://www.instechlabs.com/blog/from-pump-to-port-an-aseptic-closed-system)

```json
{
  "@context" : "http://schema.org",
  "@type" : "BlogPosting",
  "author" : {
    "@type" : "Person",
    "name" : "Wyatt Boughter"
  },
  "dateModified" : "2022-11-21T13:23:45.986Z",
  "datePublished" : "2022-07-21T11:19:44Z",
  "headline" : "Are Open Luer Connections Compromising Your Research?",
  "image" : {
    "@type" : "ImageObject",
    "height" : 675,
    "url" : "https://www.instechlabs.com/hubfs/rymed-1-1.png",
    "width" : 1200
  },
  "mainEntityOfPage" : "https://www.instechlabs.com/blog/from-pump-to-port-an-aseptic-closed-system",
  "publisher" : {
    "@type" : "Organization",
    "logo" : {
      "@type" : "ImageObject",
      "height" : 60.0,
      "url" : "https://www.instechlabs.com/hubfs/logo-instech.png",
      "width" : 106.71875
    },
    "name" : "Instech Blog"
  }
}
```